Doña Ana County (Spanish: Condado de Doña Ana) is located in the southern part of the State of New Mexico, United States. As of the 2020 U.S. Census, its population was 219,561, which makes it the second-most populated county in New Mexico. Its county seat is Las Cruces, the second-most populous municipality in New Mexico after Albuquerque, with 111,385 as of the 2020 U.S. Census.
