The Senedos, possibly an Iroquoian group, are thought to have occupied the area at one time, until they were said to have been slaughtered by the Catawba in the latter 17th century. The name of the Valley, and of the county, is most likely connected with this Native American group. It has also been attributed to General George Washington naming it in honor of John Skenandoa, an Oneida chief from New York who helped gain support of Oneida and Tuscarora warriors to aid the rebel colonists during the American Revolutionary War.
